Juvenile xanthogranuloma - Voyaga Etmagan Ksantogranuloma
☆ Germaniyaning 2022 yilgi Stiftung Warentest natijalariga ko'ra, iste'molchilarning ModelDermdan qoniqish darajasi pullik teletibbiyot maslahatlariga qaraganda bir oz pastroq bo'lgan.
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Juvenile xanthogranuloma (JXG) - bu juda keng tarqalgan holat va bolalarda non-Langerhans cell histiocytic disorder ning eng tez-tez uchraydigan turi. Taxminan 75% hollarda bu lezyonlar hayotning birinchi yilida namoyon bo'ladi va bemorlarning 15-20% dan ortig'i tug'ilishdan keyin paydo bo'ladi. Kattalarda kamdan-kam hollarda JXG odatda yigirma yoshdan o'ttiz yoshgacha bo'lgan odamlarda uchraydi va kattalardagi bemorlarning ko'pchiligida faqat bitta jarohat bor. Klinik jihatdan, u asosan yuz, bo'yin va tananing yuqori qismida bir yoki bir nechta sariq-to'q sariq-jigarrang qattiq bo'laklar yoki bo'laklar shaklida namoyon bo'ladi. Og'iz bo'shlig'ining shikastlanishi kam uchraydi, lekin tilning yon tomonlarida yoki og'izning boshqa joylarida sariq bo'lak shaklida paydo bo'lishi mumkin, bu yara va qon ketishiga olib kelishi mumkin. Teri lezyonlari odatda simptomlarni keltirib chiqarmaydi va bir necha yil davomida o'z-o'zidan o'tib ketadi. Kamdan kam bo'lsa-da, ko'zning shikastlanishi teridan tashqari eng ko'p uchraydigan muammodir, keyin esa o'pka. Ocular JXG odatda faqat bitta ko'zga ta'sir qiladi va bemorlarning 0. 5 % dan kamrog'ida uchraydi, ammo ko'z kasalliklari bilan og'riganlarning taxminan 40% tashxis qo'yilganda bir nechta teri shikastlanishiga ega.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) keng tarqalgan non-Langerhans cell histiocytoses toifasining bir qismi bo'lgan kam uchraydigan, yaxshi kasalliklardir. Ular odatda bir yoki bir nechta qizil yoki sarg'ish bo'laklar shaklida namoyon bo'ladi, ko'pincha bosh yoki bo'ynida topiladi. Ko'pgina JXGlar tug'ilish paytida yoki hayotning birinchi yilida rivojlanadi. Bu g'ayrioddiy bo'lsa-da, ba'zida ular teridan tashqarida bo'lgan joylarga ta'sir qilishi mumkin, mavjud adabiyotlarga ko'ra, ko'zning ishtiroki kuzatilishi kerak. Odatda, teridagi JXGlar o'z-o'zidan yo'qoladi va odatda davolanishni talab qilmaydi.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Ko'zning shikastlanishi JXG bilan kasallangan odamlarning 10 foizida namoyon bo'ladi va ularning ko'rish qobiliyatiga ta'sir qilishi mumkin. Teri lezyonlari odatda o'z-o'zidan yo'qolsa-da, ko'zning shikastlanishi kamdan-kam hollarda o'z-o'zidan yaxshilanadi va davolanishni talab qiladi.